Marcadores de esquizofrenia en el pelo

Knowing that, the researchers gathered hair follicles from more than 150 people and examined the expression levels of Mpst, finding that those were much higher in people diagnosed with schizophrenia. And this is how a biomarker in hair could help diagnose schizophrenia. Still, Mpst is not a 100% reliable biomarker, possibly because schizophrenia is not one but various diseases, and some patients might have some characteristics that others do not share. Not only has this discovery the potential of revolutionising disease diagnosis but also the search for novel treatment targets. But the most interesting thing by far is the finding that the cause might be an impaired cell energy metabolism as a result of epigenetic modifications leading to the over expression of Mpst and other anti-oxidative genes. But what is driving these epigenetic changes? It seems that inflammatory/oxidative threats in early brain development could produce an anti-oxidative response mediated by Mpst which would affect cell metabolism and in turn lead to schizophrenia. In conclusion, a new biomarker in hair could help early diagnosis of -some- schizophrenia cases and offers hope for new drug discovery. Now, only time will tell how far Mpst can take us. Mapping ignorance